7AEW
14-3-3 sigma bound to bis-phosphorylated aminopeptidase N (APN, CD13) via canonical and non-canonical binding motifs
This is a non-PDB format compatible entry.
Summary for 7AEW
Entry DOI | 10.2210/pdb7aew/pdb |
Related | 6xwd |
Descriptor | 14-3-3 protein sigma, Aminopeptidase N, SODIUM ION, ... (5 entities in total) |
Functional Keywords | extracellular 14-3-3, phosphorylation, aminopeptidase n, cd13, protein binding, peptide binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 34808.54 |
Authors | Kiehstaller, S.,Hennig, S. (deposition date: 2020-09-18, release date: 2020-11-04, Last modification date: 2024-01-31) |
Primary citation | Kiehstaller, S.,Ottmann, C.,Hennig, S. MMP activation-associated aminopeptidase N reveals a bivalent 14-3-3 binding motif. J.Biol.Chem., 295:18266-18275, 2020 Cited by PubMed: 33109610DOI: 10.1074/jbc.RA120.014708 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.2 Å) |
Structure validation
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