7A79

Crystal structure of RXR gamma LBD in complexes with palmitic acid and GRIP-1 peptide

Summary for 7A79

Entry DOI	10.2210/pdb7a79/pdb
Descriptor	Retinoic acid receptor RXR-gamma, Nuclear receptor coactivator 2, PALMITIC ACID, ... (4 entities in total)
Functional Keywords	rxrg, steroid hormone receptor, inhibitor, lipid binding, fatty acid, structural genomics consortium, sgc, dna binding protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	56467.54
Authors	Chaikuad, A.,Merk, D.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2020-08-27, release date: 2020-10-21, Last modification date: 2024-01-31)
Primary citation	Chaikuad, A.,Pollinger, J.,Ruhl, M.,Ni, X.,Kilu, W.,Heering, J.,Merk, D. Comprehensive Set of Tertiary Complex Structures and Palmitic Acid Binding Provide Molecular Insights into Ligand Design for RXR Isoforms. Int J Mol Sci, 21:-, 2020 Cited by PubMed: 33187070 DOI: 10.3390/ijms21228457 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation