7A79

Crystal structure of RXR gamma LBD in complexes with palmitic acid and GRIP-1 peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Retinoic acid receptor RXR-gamma	polymer	233	26234.3	2	UniProt (P48443) Pfam (PF00104)	Homo sapiens (Human)	Nuclear receptor subfamily 2 group B member 3,Retinoid X receptor gamma
2	C, D (C, D)	Nuclear receptor coactivator 2	polymer	14	1743.0	2	UniProt (Q15596)	Homo sapiens	NCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2
3	E, F (A, B)	PALMITIC ACID	non-polymer		256.4	2	Chemie (PLM)
4	G, H, I, J (A, B, C, D)	water	water		18.0	182	Chemie (HOH)

Sequence modifications

A, B: 233 - 463 (UniProt: P48443)

PDB	External Database	Details
Ser 231	-	expression tag
Met 232	-	expression tag

C, D: 471 - 484 (UniProt: Q15596)

PDB	External Database	Details
Tyr 484	Ser 699	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	55954.7
Non-Polymers*	Number of molecules	2
	Total formula weight	512.8
All*	Total formula weight	56467.5

*Water molecules are not included.