7A3U
Crystal structure of Zika virus envelope glycoprotein in complex with the divalent F(ab')2 fragment of the broadly neutralizing human antibody EDE1 C10
Summary for 7A3U
Entry DOI | 10.2210/pdb7a3u/pdb |
Related | 7A3N 7A3O 7A3P 7A3Q 7A3R 7A3S 7A3T 7CTH |
Descriptor | Envelope protein, EDE1 C10 antibody divalent F(ab')2 fragment, EDE1 C10 divalent F(ab')2 fragment, ... (4 entities in total) |
Functional Keywords | viral protein, flavivirus, class 2 fusion protein, immunocomplex, zika, antibody, f(ab')2 |
Biological source | Zika virus (ZIKV) More |
Total number of polymer chains | 3 |
Total formula weight | 96845.46 |
Authors | Sharma, A.,Vaney, M.C.,Guardado-Calvo, P.,Duquerroy, S.,Rouvinski, A.,Rey, F.A. (deposition date: 2020-08-18, release date: 2021-12-08, Last modification date: 2024-05-01) |
Primary citation | Sharma, A.,Zhang, X.,Dejnirattisai, W.,Dai, X.,Gong, D.,Wongwiwat, W.,Duquerroy, S.,Rouvinski, A.,Vaney, M.C.,Guardado-Calvo, P.,Haouz, A.,England, P.,Sun, R.,Zhou, Z.H.,Mongkolsapaya, J.,Screaton, G.R.,Rey, F.A. The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses. Cell, 184:6052-6066.e18, 2021 Cited by PubMed: 34852239DOI: 10.1016/j.cell.2021.11.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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