7A2F

Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-656

Summary for 7A2F

• Entry DOI: 10.2210/pdb7a2f/pdb
• Related: 6QGP 6QGU 7A28
• Descriptor: Phosphodiesterase, ZINC ION, MAGNESIUM ION, ... (8 entities in total)
• Functional Keywords: parasitic phosphodiesterase, hydrolase, african trypanosomiasis, sleeping sickness
• Biological source: Trypanosoma brucei
• Total number of polymer chains: 2
• Total formula weight: 82764.62

Authors

Singh, A.K.,Blaazer, A.R.,Zara, L.,de Esch, I.J.P.,Leurs, R.,Brown, D.G. (deposition date: 2020-08-17, release date: 2021-08-25, Last modification date: 2024-01-31)

• Primary citation: Singh, A.K.,Brown, D.G.; Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-656; To be published,

Experimental method

X-RAY DIFFRACTION (2 Å)