7YHN
ANTI-TUMOR AGENT Y48 IN COMPLEX WITH TUBULIN
Summary for 7YHN
Entry DOI | 10.2210/pdb7yhn/pdb |
Related | 6LS4 |
Descriptor | Tubulin alpha-1B chain, Tubulin beta chain, Stathmin, ... (9 entities in total) |
Functional Keywords | mitosis, antitumor protein, structural protein |
Biological source | Sus scrofa (pig) More |
Total number of polymer chains | 5 |
Total formula weight | 221641.89 |
Authors | |
Primary citation | Lin, S.,Du, T.,Zhang, J.,Wu, D.,Tian, H.,Zhang, K.,Jiang, L.,Lu, D.,Sheng, L.,Li, Y.,Ji, M.,Chen, X.,Xu, H. Optimization of Benzamide Derivatives as Potent and Orally Active Tubulin Inhibitors Targeting the Colchicine Binding Site. J.Med.Chem., 65:16372-16391, 2022 Cited by PubMed: 36511661DOI: 10.1021/acs.jmedchem.2c01208 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
Download full validation report