7WRQ

Structure of Human IGF1/IGFBP3/ALS Ternary Complex

Summary for 7WRQ

• Entry DOI: 10.2210/pdb7wrq/pdb
• EMDB information: 32735
• Descriptor: Insulin-like growth factor-binding protein complex acid labile subunit, Insulin-like growth factor-binding protein 3, Isoform 3 of Insulin-like growth factor I, ... (5 entities in total)
• Functional Keywords: growth, proliferation, differentiation, metabolism, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 101242.18

Authors

Kim, H.,Fu, Y.,Kim, H.M. (deposition date: 2022-01-27, release date: 2022-08-10, Last modification date: 2024-10-23)

• Primary citation: Kim, H.,Fu, Y.,Hong, H.J.,Lee, S.G.,Lee, D.S.,Kim, H.M.; Structural basis for assembly and disassembly of the IGF/IGFBP/ALS ternary complex; Nat Commun, 13:4434-, 2022; DOI: 10.1038/s41467-022-32214-2

Experimental method

ELECTRON MICROSCOPY (3.6 Å)