7WRQ
Structure of Human IGF1/IGFBP3/ALS Ternary Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Insulin-like growth factor-binding protein complex acid labile subunit | polymer | 578 | 63312.3 | 1 | UniProt (P35858) Pfam (PF01462) Pfam (PF13855) | Homo sapiens (human) | ALS |
| 2 | B (B) | Insulin-like growth factor-binding protein 3 | polymer | 264 | 28794.7 | 1 | UniProt (P17936) Pfam (PF00219) Pfam (PF00086) | Homo sapiens (human) | IBP-3,IGF-binding protein 3,IGFBP-3 |
| 3 | C (C) | Isoform 3 of Insulin-like growth factor I | polymer | 70 | 7663.8 | 1 | UniProt (P05019) Pfam (PF00049) | Homo sapiens (human) | IGF-I,Mechano growth factor,MGF,Somatomedin-C |
| 4 | D (D) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 5 | E, F, G, H (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 99770.8 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 586.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 101242.2 |
