7WN6
Cryo-EM structure of VWF D'D3 dimer (R1136M/E1143M mutant) complexed with D1D2 at 3.29 angstron resolution (2 units)
Summary for 7WN6
Entry DOI | 10.2210/pdb7wn6/pdb |
Related | 7WN4 7WPP 7WPQ 7WQT |
EMDB information | 32621 32622 32687 32688 32691 32692 32713 |
Descriptor | von Willebrand antigen 2, von Willebrand factor, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | blood, vwf, von willebrand factor, von willebrand disease, blood coagulation, blood clotting, multimer assembly, vwf assembly, d'd3 domain, d1d2 domain, d'd3 dimer, d1d2 dimer, vwf tube, repeating unit |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 547611.78 |
Authors | |
Primary citation | Shu, Z.,Zeng, J.,Xia, L.,Cai, H.,Zhou, A. Structural mechanism of VWF D'D3 dimer formation. Cell Discov, 8:14-14, 2022 Cited by PubMed: 35169124DOI: 10.1038/s41421-022-00378-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.29 Å) |
Structure validation
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