7W77
cryo-EM structure of human NaV1.3/beta1/beta2-bulleyaconitineA
Summary for 7W77
Entry DOI | 10.2210/pdb7w77/pdb |
EMDB information | 32341 |
Descriptor | Sodium channel subunit beta-1, Sodium channel subunit beta-2, Sodium channel protein type 3 subunit alpha, ... (9 entities in total) |
Functional Keywords | ion channel, drug, antagonist, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 285991.70 |
Authors | |
Primary citation | Li, X.,Xu, F.,Xu, H.,Zhang, S.,Gao, Y.,Zhang, H.,Dong, Y.,Zheng, Y.,Yang, B.,Sun, J.,Zhang, X.C.,Zhao, Y.,Jiang, D. Structural basis for modulation of human Na V 1.3 by clinical drug and selective antagonist. Nat Commun, 13:1286-1286, 2022 Cited by PubMed: 35277491DOI: 10.1038/s41467-022-28808-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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