7W77
cryo-EM structure of human NaV1.3/beta1/beta2-bulleyaconitineA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Sodium channel subunit beta-1 | polymer | 218 | 24732.1 | 1 | UniProt (Q07699) Pfam (PF07686) | Homo sapiens (human) | |
| 2 | B (C) | Sodium channel subunit beta-2 | polymer | 215 | 24355.9 | 1 | UniProt (O60939) Pfam (PF07686) | Homo sapiens (human) | Nav1.7 beta2 subunit |
| 3 | C (D) | Sodium channel protein type 3 subunit alpha | polymer | 1951 | 221036.6 | 1 | UniProt (Q9NY46) Pfam (PF00520) Pfam (PF11933) Pfam (PF06512) Pfam (PF24609) | Homo sapiens (human) | Sodium channel protein brain III subunit alpha,Sodium channel protein type III subunit alpha,Voltage-gated sodium channel subtype III,Voltage-gated sodium channel subunit alpha Nav1.3 |
| 4 | D (E) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 5 | E (F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 6 | F, G, H, I, J (B, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
| 7 | K, L, V (D) | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en | non-polymer | 544.8 | 3 | Chemie (9Z9) PubChem (134817783) | |||
| 8 | AA, BA, CA, M, N... (D) | [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | non-polymer | 718.0 | 16 | Chemie (6OU) PubChem (23727968) PubChem (3246975) PubChem (90470676) PubChem (5282290) PubChem (5283496) PubChem (123931) PubChem (5785226) PubChem (92863393) | |||
| 9 | DA (D) | [(1S,2R,3R,4R,5R,6S,8R,9S,13S,16S,17R,18R)-11-ethyl-5-hydroxy-6,16,18-trimethoxy-4-(4-methoxybenzoyl)-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecan-8-yl] acetate | non-polymer | 627.8 | 1 | Chemie (966) PubChem (176520021) PubChem (24721310) PubChem (51026623) PubChem (159311) PubChem (45358113) PubChem (53393216) PubChem (71456931) PubChem (102066559) PubChem (10031912) PubChem (122130690) PubChem (122173194) PubChem (123134773) PubChem (124605141) PubChem (124870692) PubChem (124870693) PubChem (124870694) PubChem (124870695) PubChem (146156378) PubChem (156588457) PubChem (169489453) PubChem (170996913) PubChem (170999988) PubChem (175687922) PubChem (131632412) PubChem (134129701) PubChem (163183781) PubChem (166639193) PubChem (168315402) PubChem (171991389) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 270124.6 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1010.9 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 14856.2 | |
| All* | Total formula weight | 285991.7 |
