7W77
cryo-EM structure of human NaV1.3/beta1/beta2-bulleyaconitineA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B | Sodium channel subunit beta-1 | polymer | 218 | 24732.1 | 1 | UniProt (Q07699) Pfam (PF07686) In PDB | Homo sapiens (human) | |
2 | C | Sodium channel subunit beta-2 | polymer | 215 | 24355.9 | 1 | UniProt (O60939) Pfam (PF07686) In PDB | Homo sapiens (human) | Nav1.7 beta2 subunit |
3 | D | Sodium channel protein type 3 subunit alpha | polymer | 1951 | 221036.6 | 1 | UniProt (Q9NY46) Pfam (PF00520) Pfam (PF11933) Pfam (PF06512) In PDB | Homo sapiens (human) | Sodium channel protein brain III subunit alpha,Sodium channel protein type III subunit alpha,Voltage-gated sodium channel subtype III,Voltage-gated sodium channel subunit alpha Nav1.3 |
4 | E | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
5 | F | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
6 | B, D | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
7 | D | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en | non-polymer | 544.8 | 3 | Chemie (9Z9) | |||
8 | D | [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | non-polymer | 718.0 | 16 | Chemie (6OU) | |||
9 | D | [(1S,2R,3R,4R,5R,6S,8R,9S,13S,16S,17R,18R)-11-ethyl-5-hydroxy-6,16,18-trimethoxy-4-(4-methoxybenzoyl)-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecan-8-yl] acetate | non-polymer | 627.8 | 1 | Chemie (966) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 270124.6 | |
Branched | Number of molecules | 2 |
Total formula weight | 1010.9 | |
Non-Polymers* | Number of molecules | 25 |
Total formula weight | 14856.2 | |
All* | Total formula weight | 285991.7 |