7VPX
The cryo-EM structure of the human pre-A complex
Summary for 7VPX
Entry DOI | 10.2210/pdb7vpx/pdb |
EMDB information | 32074 32075 32076 |
Descriptor | Splicing factor 3A subunit 2, Splicing factor 3A subunit 1, Splicing factor 3A subunit 3, ... (30 entities in total) |
Functional Keywords | human spliceosome, pre-a complex, prp5, a complex, u1 snrnp, u2 snrnp, splicing |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 35 |
Total formula weight | 1405823.07 |
Authors | |
Primary citation | Zhang, X.,Zhan, X.,Bian, T.,Yang, F.,Li, P.,Lu, Y.,Xing, Z.,Fan, R.,Zhang, Q.C.,Shi, Y. Structural insights into branch site proofreading by human spliceosome. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38196034DOI: 10.1038/s41594-023-01188-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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