7UAB
Human pro-meprin alpha (zymogen state)
Summary for 7UAB
Entry DOI | 10.2210/pdb7uab/pdb |
EMDB information | 26419 26420 26421 26422 26423 26424 26426 |
Descriptor | Meprin A subunit alpha, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | metalloprotease, complex, helical, extracellular, oncoprotein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 276486.89 |
Authors | Bayly-Jones, C.,Lupton, C.J.,Fritz, C.,Schlenzig, D.,Whisstock, J.C. (deposition date: 2022-03-12, release date: 2022-11-02) |
Primary citation | Bayly-Jones, C.,Lupton, C.J.,Fritz, C.,Venugopal, H.,Ramsbeck, D.,Wermann, M.,Jager, C.,de Marco, A.,Schilling, S.,Schlenzig, D.,Whisstock, J.C. Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor. Nat Commun, 13:6178-6178, 2022 Cited by PubMed: 36261433DOI: 10.1038/s41467-022-33893-7 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.7 Å) |
Structure validation
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