7UAB
Human pro-meprin alpha (zymogen state)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, D, E, H) | Meprin A subunit alpha | polymer | 587 | 67285.8 | 4 | UniProt (Q16819) Pfam (PF01400) Pfam (PF00629) Pfam (PF22486) | Homo sapiens (human) | Endopeptidase-2,N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha,PABA peptide hydrolase,PPH alpha |
| 2 | E, G, I, K, L... (B, F, I, K, L...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 7 | In PDB GlyTouCan (G42666HT) | |||
| 3 | F, H, J, N (C, G, J, N) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 4 | In PDB GlyTouCan (G21290RB) | |||
| 4 | DA, P, Q, U, V... (H, A, D, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) | |||
| 5 | AA, CA, EA, GA, R... (E, H, A, D) | CALCIUM ION | non-polymer | 40.1 | 7 | Chemie (CA) | |||
| 6 | BA, FA, S, W (E, H, A, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) |
Sequence modifications
A, D, E, H: 22 - 600 (UniProt: Q16819)
| PDB | External Database | Details |
|---|---|---|
| Trp 14 | - | expression tag |
| Ser 15 | - | expression tag |
| His 16 | - | expression tag |
| Pro 17 | - | expression tag |
| Gln 18 | - | expression tag |
| Phe 19 | - | expression tag |
| Glu 20 | - | expression tag |
| Lys 21 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 269143.3 | |
| Branched | Number of molecules | 11 |
| Total formula weight | 5253.0 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2090.6 | |
| All* | Total formula weight | 276486.9 |
