7UAB
Human pro-meprin alpha (zymogen state)
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004222 | molecular_function | metalloendopeptidase activity |
A | 0006508 | biological_process | proteolysis |
A | 0008237 | molecular_function | metallopeptidase activity |
A | 0008270 | molecular_function | zinc ion binding |
A | 0016020 | cellular_component | membrane |
D | 0004222 | molecular_function | metalloendopeptidase activity |
D | 0006508 | biological_process | proteolysis |
D | 0008237 | molecular_function | metallopeptidase activity |
D | 0008270 | molecular_function | zinc ion binding |
D | 0016020 | cellular_component | membrane |
E | 0004222 | molecular_function | metalloendopeptidase activity |
E | 0006508 | biological_process | proteolysis |
E | 0008237 | molecular_function | metallopeptidase activity |
E | 0008270 | molecular_function | zinc ion binding |
E | 0016020 | cellular_component | membrane |
H | 0004222 | molecular_function | metalloendopeptidase activity |
H | 0006508 | biological_process | proteolysis |
H | 0008237 | molecular_function | metallopeptidase activity |
H | 0008270 | molecular_function | zinc ion binding |
H | 0016020 | cellular_component | membrane |
Functional Information from PROSITE/UniProt
site_id | PS00142 |
Number of Residues | 10 |
Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. IIEHEILHAL |
Chain | Residue | Details |
A | ILE152-LEU161 |
site_id | PS00740 |
Number of Residues | 41 |
Details | MAM_1 MAM domain signature. GyFMqfsTssgsaeeaal.LesriLypkrkqqCLqFfYkmtG |
Chain | Residue | Details |
A | GLY312-GLY352 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU01211 |
Chain | Residue | Details |
A | GLU156 | |
D | GLU156 | |
E | GLU156 | |
H | GLU156 |
site_id | SWS_FT_FI2 |
Number of Residues | 12 |
Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01211 |
Chain | Residue | Details |
A | HIS155 | |
H | HIS155 | |
H | HIS159 | |
H | HIS165 | |
A | HIS159 | |
A | HIS165 | |
D | HIS155 | |
D | HIS159 | |
D | HIS165 | |
E | HIS155 | |
E | HIS159 | |
E | HIS165 |
site_id | SWS_FT_FI3 |
Number of Residues | 28 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
Chain | Residue | Details |
A | ASN140 | |
D | ASN258 | |
D | ASN414 | |
D | ASN440 | |
D | ASN447 | |
D | ASN539 | |
E | ASN140 | |
E | ASN222 | |
E | ASN258 | |
E | ASN414 | |
E | ASN440 | |
A | ASN222 | |
E | ASN447 | |
E | ASN539 | |
H | ASN140 | |
H | ASN222 | |
H | ASN258 | |
H | ASN414 | |
H | ASN440 | |
H | ASN447 | |
H | ASN539 | |
A | ASN258 | |
A | ASN414 | |
A | ASN440 | |
A | ASN447 | |
A | ASN539 | |
D | ASN140 | |
D | ASN222 |