7TJ8
Cryo-EM structure of the human Nax channel in complex with beta3 solved in nanodiscs
Summary for 7TJ8
Entry DOI | 10.2210/pdb7tj8/pdb |
EMDB information | 25919 25920 |
Descriptor | Sodium channel protein type 7 subunit alpha, Sodium channel subunit beta-3, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, ... (7 entities in total) |
Functional Keywords | sodium channel, nav, ion channel, metal transport |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 231879.18 |
Authors | Noland, C.L.,Kschonsak, M.,Ciferri, C.,Payandeh, J. (deposition date: 2022-01-14, release date: 2022-03-30) |
Primary citation | Noland, C.L.,Chua, H.C.,Kschonsak, M.,Heusser, S.A.,Braun, N.,Chang, T.,Tam, C.,Tang, J.,Arthur, C.P.,Ciferri, C.,Pless, S.A.,Payandeh, J. Structure-guided unlocking of Na X reveals a non-selective tetrodotoxin-sensitive cation channel. Nat Commun, 13:1416-1416, 2022 Cited by PubMed: 35301303DOI: 10.1038/s41467-022-28984-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
Download full validation report