7STZ
Crystal Structure of Human E-cadherin EC1-5 bound by mouse monoclonal antibody Fab mAb-1_19A11
Summary for 7STZ
Entry DOI | 10.2210/pdb7stz/pdb |
Descriptor | Cadherin-1, mAb-1_19A11 Heavy Chain, mAb-1_19A11 Light Chain, ... (10 entities in total) |
Functional Keywords | ssgcid, cadherin-1, cell adhesion, structural genomics, seattle structural genomics center for infectious disease, cell adhesion-immune system complex, cell adhesion/immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 239278.42 |
Authors | Seattle Structural Genomics Center for Infectious Disease,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2021-11-15, release date: 2022-01-26, Last modification date: 2023-10-25) |
Primary citation | Maker, A.,Bolejack, M.,Schecterson, L.,Hammerson, B.,Abendroth, J.,Edwards, T.E.,Staker, B.,Myler, P.J.,Gumbiner, B.M. Regulation of multiple dimeric states of E-cadherin by adhesion activating antibodies revealed through Cryo-EM and X-ray crystallography. Pnas Nexus, 1:pgac163-pgac163, 2022 Cited by PubMed: 36157596DOI: 10.1093/pnasnexus/pgac163 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
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