7RHQ
Cryo-EM structure of Xenopus Patched-1 in complex with GAS1 and Sonic Hedgehog
Summary for 7RHQ
Entry DOI | 10.2210/pdb7rhq/pdb |
Related | 7RHR |
EMDB information | 24466 |
Descriptor | Patched-1, PALMITIC ACID, Sonic hedgehog protein N-product, ... (10 entities in total) |
Functional Keywords | gpcr, complex, membrane protein |
Biological source | Xenopus laevis (African clawed frog) More |
Total number of polymer chains | 3 |
Total formula weight | 188925.72 |
Authors | Huang, P.,Lian, T.,Wierbowski, B.,Garcia-Linares, S.,Jiang, J.,Salic, A. (deposition date: 2021-07-18, release date: 2022-03-02, Last modification date: 2022-03-23) |
Primary citation | Huang, P.,Wierbowski, B.M.,Lian, T.,Chan, C.,Garcia-Linares, S.,Jiang, J.,Salic, A. Structural basis for catalyzed assembly of the Sonic hedgehog-Patched1 signaling complex. Dev.Cell, 57:670-685.e8, 2022 Cited by PubMed: 35231446DOI: 10.1016/j.devcel.2022.02.008 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.53 Å) |
Structure validation
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