7PHR
Structure of a fully assembled T-cell receptor engaging a tumor-associated peptide-MHC I
Summary for 7PHR
Entry DOI | 10.2210/pdb7phr/pdb |
EMDB information | 13427 |
Descriptor | T-cell receptor alpha chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, T-cell receptor beta chain, ... (10 entities in total) |
Functional Keywords | t-cell receptor, tcr, major histocompatibility complex, mhc, antigen, adaptive immunity, cancer, complex, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 11 |
Total formula weight | 202502.78 |
Authors | |
Primary citation | Susac, L.,Vuong, M.T.,Thomas, C.,von Bulow, S.,O'Brien-Ball, C.,Santos, A.M.,Fernandes, R.A.,Hummer, G.,Tampe, R.,Davis, S.J. Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC. Cell, 185:3201-3213.e19, 2022 Cited by PubMed: 35985289DOI: 10.1016/j.cell.2022.07.010 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.08 Å) |
Structure validation
Download full validation report