7PHR

Structure of a fully assembled T-cell receptor engaging a tumor-associated peptide-MHC I

Functional Information from GO Data

Chain	GOid	namespace	contents
D	0003674	molecular_function	molecular_function
D	0005575	cellular_component	cellular_component
D	0006091	biological_process	generation of precursor metabolites and energy
D	0008218	biological_process	bioluminescence
L	0006955	biological_process	immune response
L	0042612	cellular_component	MHC class I protein complex

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACRVNH

Chain	Residue	Details
L	TYR78-HIS84
H	TYR257-HIS263

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	TOPO_DOM: Extracellular => ECO:0000255

Chain	Residue	Details
Z	GLN1-LYS9
z	GLN1-LYS9
H	TYR84
H	THR143
H	LYS146
H	TYR171

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site_id	SWS_FT_FI2
Number of Residues	40
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
Z	LEU10-LEU30
z	LEU10-LEU30

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site_id	SWS_FT_FI3
Number of Residues	6
Details	CARBOHYD: N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:7918443

Chain	Residue	Details
L	LYS19
L	LYS41
L	LYS48
L	LYS58
L	LYS91
L	LYS94

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site_id	SWS_FT_FI4
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218

Chain	Residue	Details
H	ASN86

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site_id	SWS_FT_FI5
Number of Residues	2
Details	CROSSLNK: 5-imidazolinone (Ser-Gly) => ECO:0000269|PubMed:8448132

Chain	Residue	Details
D	SER183
D	GLY185

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