7ONI
Structure of Neddylated CUL5 C-terminal region-RBX2-ARIH2*
Summary for 7ONI
Entry DOI | 10.2210/pdb7oni/pdb |
EMDB information | 12995 |
Descriptor | Cullin-5, E3 ubiquitin-protein ligase ARIH2, RING-box protein 2, ... (5 entities in total) |
Functional Keywords | cul5, nedd8, ubq, ubiquitin, arih2, rbx2, ligase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 171078.74 |
Authors | Kostrhon, S.P.,prabu, J.R.,Schulman, B.A. (deposition date: 2021-05-25, release date: 2021-09-15, Last modification date: 2021-10-06) |
Primary citation | Kostrhon, S.,Prabu, J.R.,Baek, K.,Horn-Ghetko, D.,von Gronau, S.,Klugel, M.,Basquin, J.,Alpi, A.F.,Schulman, B.A. CUL5-ARIH2 E3-E3 ubiquitin ligase structure reveals cullin-specific NEDD8 activation. Nat.Chem.Biol., 17:1075-1083, 2021 Cited by PubMed: 34518685DOI: 10.1038/s41589-021-00858-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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