7OM4
Nanobody EgB4 bound to the full extracellular EGFR-EGF complex
Summary for 7OM4
Entry DOI | 10.2210/pdb7om4/pdb |
Descriptor | Epidermal growth factor receptor, Epidermal growth factor, Nanobody EgB4, ... (4 entities in total) |
Functional Keywords | egfr, nanobody, cancer, signaling, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 91682.24 |
Authors | Zeronian, M.R.,Janssen, B.J.C. (deposition date: 2021-05-21, release date: 2022-03-02, Last modification date: 2024-01-31) |
Primary citation | Zeronian, M.R.,Doulkeridou, S.,van Bergen En Henegouwen, P.M.P.,Janssen, B.J.C. Structural insights into the non-inhibitory mechanism of the anti-EGFR EgB4 nanobody. Bmc Mol Cell Biol, 23:12-12, 2022 Cited by PubMed: 35232398DOI: 10.1186/s12860-022-00412-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (6.05 Å) |
Structure validation
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