7OM4
Nanobody EgB4 bound to the full extracellular EGFR-EGF complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Epidermal growth factor receptor | polymer | 630 | 69709.3 | 1 | UniProt (P00533) Pfam (PF01030) Pfam (PF00757) Pfam (PF14843) | Homo sapiens (Human) | Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1 |
| 2 | B (C) | Epidermal growth factor | polymer | 53 | 6229.0 | 1 | UniProt (P01133) Pfam (PF00008) | Homo sapiens (Human) | Urogastrone |
| 3 | C (B) | Nanobody EgB4 | polymer | 130 | 14195.5 | 1 | Lama glama | ||
| 4 | D, E, F, G, H... (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) |
Sequence modifications
A: 1 - 621 (UniProt: P00533)
| PDB | External Database | Details |
|---|---|---|
| Ala 622 | - | expression tag |
| Ala 623 | - | expression tag |
| Ala 624 | - | expression tag |
| His 625 | - | expression tag |
| His 626 | - | expression tag |
| His 627 | - | expression tag |
| His 628 | - | expression tag |
| His 629 | - | expression tag |
| His 630 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 90133.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1548.5 | |
| All* | Total formula weight | 91682.2 |
