7NXD
Cryo-EM structure of human integrin alpha5beta1 in the half-bent conformation
Summary for 7NXD
Entry DOI | 10.2210/pdb7nxd/pdb |
Related | 3fcs 3vi3 4wk0 7NWL |
EMDB information | 12637 |
Descriptor | Integrin alpha-5, Integrin beta-1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
Functional Keywords | integrin, cell adhesion, plasma membrane protein, a5b1, alpha5beta1, focal adhesion, half-bent conformation |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 204742.42 |
Authors | Schumacher, S.,Dedden, D.,Vazquez Nunez, R.,Matoba, K.,Takagi, J.,Biertumpfel, C.,Mizuno, N. (deposition date: 2021-03-18, release date: 2021-08-25) |
Primary citation | Schumacher, S.,Dedden, D.,Nunez, R.V.,Matoba, K.,Takagi, J.,Biertumpfel, C.,Mizuno, N. Structural insights into integrin alpha 5 beta 1 opening by fibronectin ligand. Sci Adv, 7:-, 2021 Cited by PubMed: 33962943DOI: 10.1126/sciadv.abe9716 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.6 Å) |
Structure validation
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