7MXI
IgE-Fc in complex with DARPins E2_79 and E3_53
Summary for 7MXI
Entry DOI | 10.2210/pdb7mxi/pdb |
Descriptor | IgE Fc, DARPin E3_53, Anti-IgE Inhibitor E2_79, ... (5 entities in total) |
Functional Keywords | ige, darpin, allergy, inhibitor, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 125455.18 |
Authors | Pennington, L.F.,Jardetzky, T.J. (deposition date: 2021-05-19, release date: 2021-07-28, Last modification date: 2023-10-18) |
Primary citation | Pennington, L.F.,Gasser, P.,Brigger, D.,Guntern, P.,Eggel, A.,Jardetzky, T.S. Structure-guided design of ultrapotent disruptive IgE inhibitors to rapidly terminate acute allergic reactions. J.Allergy Clin.Immunol., 148:1049-1060, 2021 Cited by PubMed: 33991582DOI: 10.1016/j.jaci.2021.03.050 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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