7MFG
Cryo-EM structure of the VRC310 clinical trial, vaccine-elicited, human antibody 310-030-1D06 Fab in complex with an H1 NC99 HA trimer
Summary for 7MFG
Entry DOI | 10.2210/pdb7mfg/pdb |
Related | 7L0L |
EMDB information | 23816 |
Descriptor | Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, 310-030-1D06 Heavy, ... (6 entities in total) |
Functional Keywords | vrc, immune system, vrc310, h1, fab, flu, immune system-viral protein complex, viral protein-immune system complex, viral protein/immune system |
Biological source | Influenza A virus More |
Total number of polymer chains | 12 |
Total formula weight | 265395.95 |
Authors | Gorman, J.,Kwong, P.D. (deposition date: 2021-04-09, release date: 2021-11-03, Last modification date: 2024-10-09) |
Primary citation | Andrews, S.F.,Raab, J.E.,Gorman, J.,Gillespie, R.A.,Cheung, C.S.F.,Rawi, R.,Cominsky, L.Y.,Boyington, J.C.,Creanga, A.,Shen, C.H.,Harris, D.R.,Olia, A.S.,Nazzari, A.F.,Zhou, T.,Houser, K.V.,Chen, G.L.,Mascola, J.R.,Graham, B.S.,Kanekiyo, M.,Ledgerwood, J.E.,Kwong, P.D.,McDermott, A.B. A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination. Nat Med, 28:373-382, 2022 Cited by PubMed: 35115707DOI: 10.1038/s41591-021-01636-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.87 Å) |
Structure validation
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