7LPX
Crystal Structure of HIV-1 RT in Complex with NBD-14270
Summary for 7LPX
Entry DOI | 10.2210/pdb7lpx/pdb |
Descriptor | Reverse transcriptase p66, Reverse transcriptase p51, SULFATE ION, ... (5 entities in total) |
Functional Keywords | human immunodeficiency virus 1, non nucleotide-reverse transcriptase inhibitor, transferase, transferase-inhibitor complex, transferase/inhibitor |
Biological source | Human immunodeficiency virus type 1 (HIV-1) More |
Total number of polymer chains | 2 |
Total formula weight | 114895.46 |
Authors | Losada, N.,Ruiz, F.X.,Arnold, E. (deposition date: 2021-02-12, release date: 2021-11-17, Last modification date: 2023-10-18) |
Primary citation | Losada, N.,Ruiz, F.X.,Curreli, F.,Gruber, K.,Pilch, A.,Das, K.,Debnath, A.K.,Arnold, E. HIV-1 gp120 Antagonists Also Inhibit HIV-1 Reverse Transcriptase by Bridging the NNRTI and NRTI Sites. J.Med.Chem., 64:16530-16540, 2021 Cited by PubMed: 34735153DOI: 10.1021/acs.jmedchem.1c01104 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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