7BBJ
CD73 in complex with the humanized antagonistic antibody mAb19
Summary for 7BBJ
Entry DOI | 10.2210/pdb7bbj/pdb |
Descriptor | 5'-nucleotidase, heavy chain mAb19, light chain mAB19, ... (6 entities in total) |
Functional Keywords | antibody complex, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 216423.55 |
Authors | Boettcher, J.,Han, F. (deposition date: 2020-12-17, release date: 2021-12-29, Last modification date: 2024-01-31) |
Primary citation | Wurm, M.,Schaaf, O.,Reutner, K.,Ganesan, R.,Mostbock, S.,Pelster, C.,Bottcher, J.,de Andrade Pereira, B.,Taubert, C.,Alt, I.,Serna, G.,Auguste, A.,Stadermann, K.B.,Delic, D.,Han, F.,Capdevila, J.,Nuciforo, P.G.,Kroe-Barrett, R.,Adam, P.J.,Vogt, A.B.,Hofmann, I. A Novel Antagonistic CD73 Antibody for Inhibition of the Immunosuppressive Adenosine Pathway. Mol.Cancer Ther., 20:2250-2261, 2021 Cited by PubMed: 34482286DOI: 10.1158/1535-7163.MCT-21-0107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.72 Å) |
Structure validation
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