7B26
CirpA1 in complex with pseudo-monomeric Properdin lacking TSR2-3
Summary for 7B26
Entry DOI | 10.2210/pdb7b26/pdb |
Related | 7B28 7B29 7B2A 7B2D |
Descriptor | Properdin, CirpA1, beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose, ... (5 entities in total) |
Functional Keywords | inhibitor, complement, tick, complex, immunosuppressant |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 64349.33 |
Authors | Lea, S.M.,Johnson, S.,Braunger, K. (deposition date: 2020-11-26, release date: 2021-12-08, Last modification date: 2024-07-24) |
Primary citation | Braunger, K.,Ahn, J.,Jore, M.M.,Johnson, S.,Tang, T.T.L.,Pedersen, D.V.,Andersen, G.R.,Lea, S.M. Structure and function of a family of tick-derived complement inhibitors targeting properdin. Nat Commun, 13:317-317, 2022 Cited by PubMed: 35031611DOI: 10.1038/s41467-021-27920-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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