6ZIZ
CRYSTAL STRUCTURE OF NRAS Q61R IN COMPLEX WITH GTP AND COMPOUND 18
Summary for 6ZIZ
| Entry DOI | 10.2210/pdb6ziz/pdb |
| Descriptor | GTPase NRas, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total) |
| Functional Keywords | gtpase, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 41020.28 |
| Authors | Kessler, D.,Fischer, G.,Boettcher, J. (deposition date: 2020-06-26, release date: 2020-08-19, Last modification date: 2024-01-31) |
| Primary citation | Kessler, D.,Bergner, A.,Bottcher, J.,Fischer, G.,Dobel, S.,Hinkel, M.,Mullauer, B.,Weiss-Puxbaum, A.,McConnell, D.B. Drugging all RAS isoforms with one pocket. Future Med Chem, 12:1911-1923, 2020 Cited by PubMed: 32779487DOI: 10.4155/fmc-2020-0221 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.785 Å) |
Structure validation
Download full validation report
