6Z49
Crystal structure of deubiquitinase Mindy2
Summary for 6Z49
| Entry DOI | 10.2210/pdb6z49/pdb |
| Descriptor | Ubiquitin carboxyl-terminal hydrolase MINDY-2, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... (5 entities in total) |
| Functional Keywords | hydrolase, cysteine protease, isopeptidase and ubiquitin binding |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 4 |
| Total formula weight | 125562.58 |
| Authors | Abdul Rehman, S.A.,Kulathu, Y. (deposition date: 2020-05-23, release date: 2021-06-02, Last modification date: 2024-01-24) |
| Primary citation | Abdul Rehman, S.A.,Armstrong, L.A.,Lange, S.M.,Kristariyanto, Y.A.,Grawert, T.W.,Knebel, A.,Svergun, D.I.,Kulathu, Y. Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2. Mol.Cell, 81:4176-4190.e6, 2021 Cited by PubMed: 34529927DOI: 10.1016/j.molcel.2021.08.024 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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