6Z49
Crystal structure of deubiquitinase Mindy2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
| A | 1990380 | molecular_function | K48-linked deubiquitinase activity |
| B | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
| B | 1990380 | molecular_function | K48-linked deubiquitinase activity |
| C | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
| C | 1990380 | molecular_function | K48-linked deubiquitinase activity |
| D | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
| D | 1990380 | molecular_function | K48-linked deubiquitinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 602 |
| Chain | Residue |
| A | PHE349 |
| A | TYR351 |
| A | CYS355 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 601 |
| Chain | Residue |
| B | GLY345 |
| B | VAL346 |
| B | ARG347 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 602 |
| Chain | Residue |
| B | TRP279 |
| B | LYS282 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue PG4 B 605 |
| Chain | Residue |
| B | LYS280 |
| B | LEU361 |
| B | ALA278 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue CL C 601 |
| Chain | Residue |
| C | ALA278 |
| C | LYS280 |
| C | HOH709 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue CL D 601 |
| Chain | Residue |
| B | LYS456 |
| D | LYS473 |
| D | ARG496 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue CL D 602 |
| Chain | Residue |
| D | GLN422 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue PEG D 603 |
| Chain | Residue |
| A | PRO285 |
| D | ASN254 |
| D | TRP279 |
| D | LYS282 |
| D | HOH708 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"UniProtKB","id":"Q8N5J2","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"Q8N5J2","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
