6YEJ
Cryo-EM structure of the Full-length disease type human Huntingtin
Summary for 6YEJ
Entry DOI | 10.2210/pdb6yej/pdb |
EMDB information | 10793 4937 |
Descriptor | Huntingtin (1 entity in total) |
Functional Keywords | multivalent scaffold platform, protein binding, structural protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 355278.72 |
Authors | Tame, G.,Jung, T.,Dal Perraro, M.,Hebert, H.,Song, J. (deposition date: 2020-03-24, release date: 2020-12-16) |
Primary citation | Jung, T.,Shin, B.,Tamo, G.,Kim, H.,Vijayvargia, R.,Leitner, A.,Marcaida, M.J.,Astorga-Wells, J.,Jung, R.,Aebersold, R.,Peraro, M.D.,Hebert, H.,Seong, I.S.,Song, J.J. The Polyglutamine Expansion at the N-Terminal of Huntingtin Protein Modulates the Dynamic Configuration and Phosphorylation of the C-Terminal HEAT Domain. Structure, 28:1035-1050.e8, 2020 Cited by PubMed: 32668197DOI: 10.1016/j.str.2020.06.008 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (18.2 Å) |
Structure validation
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