6Y54

Crystal structure of a Neisseria meningitidis serogroup A capsular oligosaccharide bound to a functional Fab

Summary for 6Y54

• Entry DOI: 10.2210/pdb6y54/pdb
• Descriptor: Fab A1.1 H chain, Fab A1.1 L chain, IODIDE ION, ... (8 entities in total)
• Functional Keywords: antigen-antibody complex, epitope mapping, carbohydrate, glycan, immune system
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 6
• Total formula weight: 150896.24

Authors

Dello Iacono, L.,Henriques, P.,Adamo, R. (deposition date: 2020-02-24, release date: 2020-10-07, Last modification date: 2024-01-24)

• Primary citation: Henriques, P.,Dello Iacono, L.,Gimeno, A.,Biolchi, A.,Romano, M.R.,Arda, A.,Bernardes, G.J.L.,Jimenez-Barbero, J.,Berti, F.,Rappuoli, R.,Adamo, R.; Structure of a protective epitope reveals the importance of acetylation of Neisseria meningitidis serogroup A capsular polysaccharide.; Proc.Natl.Acad.Sci.USA, 117:29795-29802, 2020; PubMed: 33158970; DOI: 10.1073/pnas.2011385117

Experimental method

X-RAY DIFFRACTION (2.67 Å)