6X6E

Glucocorticoid Receptor DNA binding domain in complex with methylated precursor for a modern recognition element (methylated pre-GBS)

Summary for 6X6E

• Entry DOI: 10.2210/pdb6x6e/pdb
• Descriptor: Glucocorticoid receptor, DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*GP*GP*AP*GP*(5CM)P*GP*TP*TP*CP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*GP*AP*AP*CP*GP*CP*TP*CP*(5CM)P*GP*TP*TP*CP*TP*G)-3'), ... (5 entities in total)
• Functional Keywords: gr, pre-gbs, dna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 28096.65

Authors

Liu, X.,Ortlund, E.A. (deposition date: 2020-05-28, release date: 2021-06-02, Last modification date: 2023-10-18)

• Primary citation: Liu, X.,Weikum, E.R.,Tilo, D.,Vinson, C.,Ortlund, E.A.; Structural basis for glucocorticoid receptor recognition of both unmodified and methylated binding sites, precursors of a modern recognition element.; Nucleic Acids Res., 49:8923-8933, 2021; PubMed: 34289059; DOI: 10.1093/nar/gkab605

Experimental method

X-RAY DIFFRACTION (2 Å)