6WK6

Crystal structure of human polymerase eta complexed with Xanthine containing DNA

Summary for 6WK6

• Entry DOI: 10.2210/pdb6wk6/pdb
• Descriptor: DNA polymerase eta, DNA (5'-D(*CP*AP*TP*(3ZO)P*CP*TP*CP*AP*CP*AP*CP*T)-3'), DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), ... (6 entities in total)
• Functional Keywords: dpo4, y-family dna polymerase, translesion synthesis, transferase, extension, dna binding protein, dna binding protein-dna complex
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 54930.18

Authors

Jung, H.,Lee, S. (deposition date: 2020-04-15, release date: 2021-01-06, Last modification date: 2023-10-18)

• Primary citation: Jung, H.,Hawkins, M.,Lee, S.; Structural insights into the bypass of the major deaminated purines by translesion synthesis DNA polymerase.; Biochem.J., 477:4797-4810, 2020; PubMed: 33258913; DOI: 10.1042/BCJ20200800

Experimental method

X-RAY DIFFRACTION (2.35 Å)