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6WK6

Crystal structure of human polymerase eta complexed with Xanthine containing DNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase etapolymer43248325.41UniProt (Q9Y253)
Pfam (PF00817)
Pfam (PF21704)
Pfam (PF11799)
Homo sapiens (Human)RAD30 homolog A,Xeroderma pigmentosum variant type protein
2B
(T)
DNA (5'-D(*CP*AP*TP*(3ZO)P*CP*TP*CP*AP*CP*AP*CP*T)-3')polymer123583.31Homo sapiens
3C
(P)
DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3')polymer82506.71Homo sapiens
4D
(A)
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidinenon-polymer466.21Chemie (0KX)
5E, F
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
6G, H
(A, P)
waterwater18.060Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight54415.4
Non-Polymers*Number of molecules3
Total formula weight514.8
All*Total formula weight54930.2
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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