6WDZ
Porcine circovirus 2 Rep domain complexed with a single-stranded DNA 10-mer comprising the cleavage site
Summary for 6WDZ
Entry DOI | 10.2210/pdb6wdz/pdb |
Descriptor | DNA (5'-D(*TP*AP*GP*TP*AP*TP*TP*AP*CP*C)-3'), ATP-dependent helicase Rep, MANGANESE (II) ION, ... (5 entities in total) |
Functional Keywords | huh-tag, huh motif, rep domain, viral protein, single stranded dna, ssdna, ssdna binding, replication, dna binding protein, replication-dna complex, replication/dna |
Biological source | Porcine circovirus 2 (PCV2) More |
Total number of polymer chains | 7 |
Total formula weight | 52144.94 |
Authors | Litzau, L.A.,Tompkins, K.,Shi, K.,Nelson, A.,Evans III, R.L.,Gordon, W.R. (deposition date: 2020-04-01, release date: 2020-12-16, Last modification date: 2023-10-18) |
Primary citation | Tompkins, K.J.,Houtti, M.,Litzau, L.A.,Aird, E.J.,Everett, B.A.,Nelson, A.T.,Pornschloegl, L.,Limon-Swanson, L.K.,Evans, R.L.,Evans, K.,Shi, K.,Aihara, H.,Gordon, W.R. Molecular underpinnings of ssDNA specificity by Rep HUH-endonucleases and implications for HUH-tag multiplexing and engineering. Nucleic Acids Res., 49:1046-1064, 2021 Cited by PubMed: 33410911DOI: 10.1093/nar/gkaa1248 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.03 Å) |
Structure validation
Download full validation report