6WCQ
Structure of a substrate-bound DQC ubiquitin ligase
Summary for 6WCQ
Entry DOI | 10.2210/pdb6wcq/pdb |
Related | 6W66 |
EMDB information | 21617 |
Descriptor | S-phase kinase-associated protein 1, F-box/LRR-repeat protein 17, Kelch-like ECH-associated protein 1, ... (4 entities in total) |
Functional Keywords | ubiquitin, e3-ligase, multiprotein complex, substrate recognition, ligase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 183750.01 |
Authors | Mena, E.L.,Jevtic, P.,Greber, B.J.,Gee, C.L.,Lew, B.G.,Akopian, D.,Nogales, E.,Kuriyan, J.,Rape, M. (deposition date: 2020-03-31, release date: 2020-08-19, Last modification date: 2024-03-06) |
Primary citation | Mena, E.L.,Jevtic, P.,Greber, B.J.,Gee, C.L.,Lew, B.G.,Akopian, D.,Nogales, E.,Kuriyan, J.,Rape, M. Structural basis for dimerization quality control. Nature, 586:452-456, 2020 Cited by PubMed: 32814905DOI: 10.1038/s41586-020-2636-7 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (8.5 Å) |
Structure validation
Download full validation report