6WCQ

Structure of a substrate-bound DQC ubiquitin ligase

Summary for 6WCQ

• Entry DOI: 10.2210/pdb6wcq/pdb
• Related: 6W66
• EMDB information: 21617
• Descriptor: S-phase kinase-associated protein 1, F-box/LRR-repeat protein 17, Kelch-like ECH-associated protein 1, ... (4 entities in total)
• Functional Keywords: ubiquitin, e3-ligase, multiprotein complex, substrate recognition, ligase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 183750.01

Authors

Mena, E.L.,Jevtic, P.,Greber, B.J.,Gee, C.L.,Lew, B.G.,Akopian, D.,Nogales, E.,Kuriyan, J.,Rape, M. (deposition date: 2020-03-31, release date: 2020-08-19, Last modification date: 2024-03-06)

• Primary citation: Mena, E.L.,Jevtic, P.,Greber, B.J.,Gee, C.L.,Lew, B.G.,Akopian, D.,Nogales, E.,Kuriyan, J.,Rape, M.; Structural basis for dimerization quality control.; Nature, 586:452-456, 2020; PubMed: 32814905; DOI: 10.1038/s41586-020-2636-7

Experimental method

ELECTRON MICROSCOPY (8.5 Å)