6WC2
Crystal Structure of a Ternary MEF2 Chimera/NKX2-5/myocardin enhancer DNA Complex
Summary for 6WC2
Entry DOI | 10.2210/pdb6wc2/pdb |
Descriptor | MEF2 Chimera,Myocyte-specific enhancer factor 2B,Myocyte-specific enhancer factor 2A, Myocardin Enhancer DNA, Homeobox protein Nkx-2.5, ... (5 entities in total) |
Functional Keywords | transcription factor, dna binding protein, cardiogenesis, carcinogenesis, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 15 |
Total formula weight | 129719.01 |
Authors | |
Primary citation | Lei, X.,Zhao, J.,Sagendorf, J.M.,Rajashekar, N.,Xu, J.,Dantas Machado, A.C.,Sen, C.,Rohs, R.,Feng, P.,Chen, L. Crystal Structures of Ternary Complexes of MEF2 and NKX2-5 Bound to DNA Reveal a Disease Related Protein-Protein Interaction Interface. J.Mol.Biol., 432:5499-5508, 2020 Cited by PubMed: 32681840DOI: 10.1016/j.jmb.2020.07.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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