6WBV
Structure of human ferroportin bound to hepcidin and cobalt in lipid nanodisc
Summary for 6WBV
Entry DOI | 10.2210/pdb6wbv/pdb |
Related | 6W4S |
EMDB information | 21539 21599 |
Descriptor | Hepcidin, Solute carrier family 40 member 1, Fab45D8 Light Chain, ... (7 entities in total) |
Functional Keywords | ferroportin, transporter, iron, hepcidin, translocase-immune system-hormone complex, translocase/immune system/hormone |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 118042.24 |
Authors | Billesboelle, C.B.,Azumaya, C.M.,Gonen, S.,Powers, A.,Kretsch, R.C.,Schneider, S.,Arvedson, T.,Dror, R.O.,Cheng, Y.,Manglik, A. (deposition date: 2020-03-27, release date: 2020-09-09, Last modification date: 2020-11-11) |
Primary citation | Billesbolle, C.B.,Azumaya, C.M.,Kretsch, R.C.,Powers, A.S.,Gonen, S.,Schneider, S.,Arvedson, T.,Dror, R.O.,Cheng, Y.,Manglik, A. Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms. Nature, 586:807-811, 2020 Cited by PubMed: 32814342DOI: 10.1038/s41586-020-2668-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.5 Å) |
Structure validation
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