6VJD
Estrogen Receptor Alpha Ligand Binding Domain in Complex with Lasofoxifene
Summary for 6VJD
Entry DOI | 10.2210/pdb6vjd/pdb |
Descriptor | Estrogen receptor, (5R,6S)-6-PHENYL-5-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]-5,6,7,8-TETRAHYDRONAPHTHALEN-2-OL (3 entities in total) |
Functional Keywords | estrogen receptor, lasofoxifene, hormone, serm, antiestrogen, transcription |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 115147.17 |
Authors | Fanning, S.W.,Greene, G.L. (deposition date: 2020-01-15, release date: 2020-02-26, Last modification date: 2023-10-11) |
Primary citation | Fanning, S.W. Estrogen Receptor Alpha To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report