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6VJD

Estrogen Receptor Alpha Ligand Binding Domain in Complex with Lasofoxifene

Summary for 6VJD
Entry DOI10.2210/pdb6vjd/pdb
DescriptorEstrogen receptor, (5R,6S)-6-PHENYL-5-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]-5,6,7,8-TETRAHYDRONAPHTHALEN-2-OL (3 entities in total)
Functional Keywordsestrogen receptor, lasofoxifene, hormone, serm, antiestrogen, transcription
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total formula weight115147.17
Authors
Fanning, S.W.,Greene, G.L. (deposition date: 2020-01-15, release date: 2020-02-26, Last modification date: 2023-10-11)
Primary citationFanning, S.W.
Estrogen Receptor Alpha
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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