6VEL

Crystal Structure of Human E-cadherin bound by mouse monoclonal antibody 66E8Fab

6VEL の概要

• エントリーDOI: 10.2210/pdb6vel/pdb
• 分子名称: 66E8 Fab Heavy Chain, 66E8 Fab Light Chain, Ubiquitin-like protein SMT3,Cadherin-1, ... (6 entities in total)
• 機能のキーワード: ssgcid, cadherin, e-cadherin, antibody, structural genomics, seattle structural genomics center for infectious disease, cell adhesion, cell adhesion-immune system complex, cell adhesion/immune system
• 由来する生物種: Mus musculus; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 89540.77

構造登録者

Seattle Structural Genomics Center for Infectious Disease,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2020-01-02, 公開日: 2020-01-29, 最終更新日: 2023-10-25)

• 主引用文献: Maker, A.,Bolejack, M.,Schecterson, L.,Hammerson, B.,Abendroth, J.,Edwards, T.E.,Staker, B.,Myler, P.J.,Gumbiner, B.M.; Regulation of multiple dimeric states of E-cadherin by adhesion activating antibodies revealed through Cryo-EM and X-ray crystallography.; Pnas Nexus, 1:pgac163-pgac163, 2022; PubMed: 36157596; DOI: 10.1093/pnasnexus/pgac163

実験手法

X-RAY DIFFRACTION (2.65 Å)