6VDB
SETD2 in complex with a H3-variant super-substrate peptide
Summary for 6VDB
Entry DOI | 10.2210/pdb6vdb/pdb |
Descriptor | Histone-lysine N-methyltransferase SETD2, ALA-PRO-ARG-PHE-GLY-GLY-VAL-MET-ARG-PRO-ASN-ARG, S-ADENOSYL-L-HOMOCYSTEINE, ... (7 entities in total) |
Functional Keywords | transferase, structural genomics, structural genomics consortium, sgc |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 37726.69 |
Authors | Beldar, S.,Tempel, W.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,Jeltsch, A.,Min, J.,Structural Genomics Consortium,Structural Genomics Consortium (SGC) (deposition date: 2019-12-24, release date: 2020-01-29, Last modification date: 2023-10-11) |
Primary citation | Schuhmacher, M.K.,Beldar, S.,Khella, M.S.,Brohm, A.,Ludwig, J.,Tempel, W.,Weirich, S.,Min, J.,Jeltsch, A. Sequence specificity analysis of the SETD2 protein lysine methyltransferase and discovery of a SETD2 super-substrate. Commun Biol, 3:511-511, 2020 Cited by PubMed: 32939018DOI: 10.1038/s42003-020-01223-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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