6UXJ

Structure of serine hydroxymethyltransferase 8 from Glycine max cultivar Essex complexed with PLP-glycine and 5-formyltetrahydrofolate

Summary for 6UXJ

Entry DOI	10.2210/pdb6uxj/pdb
Descriptor	Serine hydroxymethyltransferase, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, ... (5 entities in total)
Functional Keywords	folate metabolism, methyltransferase, soybean cyst nematode infection resistance, cytoplasmic enzyme, plant protein, transferase
Biological source	Glycine max (Soybean)
Total number of polymer chains	4
Total formula weight	212402.08
Authors	Korasick, D.A.,Tanner, J.J.,Beamer, L.J. (deposition date: 2019-11-07, release date: 2020-02-12, Last modification date: 2023-10-11)
Primary citation	Korasick, D.A.,Kandoth, P.K.,Tanner, J.J.,Mitchum, M.G.,Beamer, L.J. Impaired folate binding of serine hydroxymethyltransferase 8 from soybean underlies resistance to the soybean cyst nematode. J.Biol.Chem., 295:3708-3718, 2020 Cited by PubMed: 32014996 DOI: 10.1074/jbc.RA119.012256 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation