6UPM
Crystal structure of T467A variant of cytosolic fumarate hydratase from Leishmania major in a complex with S-malate
Summary for 6UPM
Entry DOI | 10.2210/pdb6upm/pdb |
Related | 6UNZ 6UO0 6UOI 6UOJ 6UP9 6UPO 6UQ8 6UQ9 6UQB 6UQL 6UQM 6UQN |
Descriptor | Fumarate hydratase 2, IRON/SULFUR CLUSTER, (2S)-2-hydroxybutanedioic acid, ... (5 entities in total) |
Functional Keywords | fumarate hydratase, fumarase, leishmania major, substrate, s-malate, variant t467a, lyase |
Biological source | Leishmania major strain Friedlin |
Total number of polymer chains | 2 |
Total formula weight | 134122.53 |
Authors | Feliciano, P.R.,Drennan, C.L. (deposition date: 2019-10-17, release date: 2019-12-04, Last modification date: 2023-10-11) |
Primary citation | Feliciano, P.R.,Drennan, C.L. Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major. Biochemistry, 58:5011-5021, 2019 Cited by PubMed: 31743022DOI: 10.1021/acs.biochem.9b00923 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.03 Å) |
Structure validation
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