6UO7
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 1 (CD1) K330L mutant complexed with AR-42
Summary for 6UO7
Entry DOI | 10.2210/pdb6uo7/pdb |
Descriptor | Histone deacetylase 6, ZINC ION, POTASSIUM ION, ... (5 entities in total) |
Functional Keywords | histone deacetylase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Danio rerio (Zebrafish) |
Total number of polymer chains | 1 |
Total formula weight | 40734.54 |
Authors | Osko, J.D.,Christianson, D.W. (deposition date: 2019-10-14, release date: 2019-12-04, Last modification date: 2023-10-11) |
Primary citation | Osko, J.D.,Christianson, D.W. Structural Basis of Catalysis and Inhibition of HDAC6 CD1, the Enigmatic Catalytic Domain of Histone Deacetylase 6. Biochemistry, 58:4912-4924, 2019 Cited by PubMed: 31755702DOI: 10.1021/acs.biochem.9b00934 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.39501316141 Å) |
Structure validation
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