6UNP
Crystal structure of the kinase domain of BMPR2-D485G
Summary for 6UNP
Entry DOI | 10.2210/pdb6unp/pdb |
Descriptor | Bone morphogenetic protein receptor type-2, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | kinase, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 85829.27 |
Authors | |
Primary citation | Agnew, C.,Ayaz, P.,Kashima, R.,Loving, H.S.,Ghatpande, P.,Kung, J.E.,Underbakke, E.S.,Shan, Y.,Shaw, D.E.,Hata, A.,Jura, N. Structural basis for ALK2/BMPR2 receptor complex signaling through kinase domain oligomerization. Nat Commun, 12:4950-4950, 2021 Cited by PubMed: 34400635DOI: 10.1038/s41467-021-25248-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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