6UKT
Cryo-EM structure of mammalian Ric-8A:Galpha(i):nanobody complex
Summary for 6UKT
Entry DOI | 10.2210/pdb6ukt/pdb |
EMDB information | 20812 |
Descriptor | Resistance to inhibitors of cholinesterase 8 homolog A (C. elegans), Guanine nucleotide-binding protein G(i) subunit alpha-1, NB8109, ... (6 entities in total) |
Functional Keywords | ric-8a, g protein, gef, signaling protein |
Biological source | Rattus norvegicus (Rat) More |
Total number of polymer chains | 6 |
Total formula weight | 150597.49 |
Authors | Mou, T.C.,Zhang, K.,Johnston, J.D.,Chiu, W.,Sprang, S.R. (deposition date: 2019-10-05, release date: 2020-03-11) |
Primary citation | McClelland, L.J.,Zhang, K.,Mou, T.C.,Johnston, J.,Yates-Hansen, C.,Li, S.,Thomas, C.J.,Doukov, T.I.,Triest, S.,Wohlkonig, A.,Tall, G.G.,Steyaert, J.,Chiu, W.,Sprang, S.R. Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to G alpha i1. Nat Commun, 11:1077-1077, 2020 Cited by PubMed: 32103024DOI: 10.1038/s41467-020-14943-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.87 Å) |
Structure validation
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