6TWB
Crystal Structure of the Catalytic Domain of Coagulation Factor XIa in Complex with Double Bridged Peptide F19
Summary for 6TWB
Entry DOI | 10.2210/pdb6twb/pdb |
Descriptor | Coagulation factor XI, Double Bridged Peptide F19, AMMONIUM ION, ... (4 entities in total) |
Functional Keywords | protease, coagulation factors, inhibitor, double bridged peptide, phage display, blood clotting |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 60790.21 |
Authors | Kong, X.D.,Pojer, F.,Heinis, C. (deposition date: 2020-01-13, release date: 2020-05-13, Last modification date: 2024-01-24) |
Primary citation | Kong, X.D.,Moriya, J.,Carle, V.,Pojer, F.,Abriata, L.A.,Deyle, K.,Heinis, C. De novo development of proteolytically resistant therapeutic peptides for oral administration. Nat Biomed Eng, 4:560-571, 2020 Cited by PubMed: 32393891DOI: 10.1038/s41551-020-0556-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.91 Å) |
Structure validation
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